prikaz prve stranice dokumenta Antifungal Activities of Fluorinated Pyrazole Aldehydes on Phytopathogenic Fungi, and Their Effect on Entomopathogenic Nematodes, and Soil-Beneficial Bacteria
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Antifungal Activities of Fluorinated Pyrazole Aldehydes on Phytopathogenic Fungi, and Their Effect on Entomopathogenic Nematodes, and Soil-Beneficial Bacteria
International Journal o f Molecular Sciences, 24 (2023), 11; 9335. https://doi.org/10.3390/ijms24119335
Rastija, Vesna; Vrandečić, Karolina; Ćosić, Jasenka; Kanižai Šarić, Gabriella; Majić, Ivana; Agić, Dejan; Šubarić, Domagoj; Karnaš, Maja; Bešlo, Drago; Grahmbhatt, H.; Komar, M.

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Rastija, V., Vrandečić, K., Ćosić, J., Kanižai Šarić, G., Majić, I., Agić, D. ... Komar, M. (2023). Antifungal Activities of Fluorinated Pyrazole Aldehydes on Phytopathogenic Fungi, and Their Effect on Entomopathogenic Nematodes, and Soil-Beneficial Bacteria. International Journal o f Molecular Sciences, 24. (11). doi: 10.3390/ijms24119335

Rastija, Vesna, et al. "Antifungal Activities of Fluorinated Pyrazole Aldehydes on Phytopathogenic Fungi, and Their Effect on Entomopathogenic Nematodes, and Soil-Beneficial Bacteria." International Journal o f Molecular Sciences, vol. 24, br. 11, 2023. https://doi.org/10.3390/ijms24119335

Rastija, Vesna, Karolina Vrandečić, Jasenka Ćosić, Gabriella Kanižai Šarić, Ivana Majić, Dejan Agić, Domagoj Šubarić, et al. "Antifungal Activities of Fluorinated Pyrazole Aldehydes on Phytopathogenic Fungi, and Their Effect on Entomopathogenic Nematodes, and Soil-Beneficial Bacteria." International Journal o f Molecular Sciences 24, br. 11 (2023). https://doi.org/10.3390/ijms24119335

Rastija, V., et al. (2023) 'Antifungal Activities of Fluorinated Pyrazole Aldehydes on Phytopathogenic Fungi, and Their Effect on Entomopathogenic Nematodes, and Soil-Beneficial Bacteria', International Journal o f Molecular Sciences, 24(11). doi: 10.3390/ijms24119335

Rastija V, Vrandečić K, Ćosić J, Kanižai Šarić G, Majić I, Agić D, i sur.. Antifungal Activities of Fluorinated Pyrazole Aldehydes on Phytopathogenic Fungi, and Their Effect on Entomopathogenic Nematodes, and Soil-Beneficial Bacteria. International Journal o f Molecular Sciences [Internet]. 26.05.2023. [pristupljeno 23.11.2024.];24(11). doi: 10.3390/ijms24119335

V. Rastija, et al., "Antifungal Activities of Fluorinated Pyrazole Aldehydes on Phytopathogenic Fungi, and Their Effect on Entomopathogenic Nematodes, and Soil-Beneficial Bacteria", International Journal o f Molecular Sciences, vol. 24, br. 11, Svibanj 2023. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:151:314252. [Citirano: 23.11.2024.]

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Podaci o radu
Naslov (engleski)Antifungal Activities of Fluorinated Pyrazole Aldehydes on Phytopathogenic Fungi, and Their Effect on Entomopathogenic Nematodes, and Soil-Beneficial Bacteria
AutorVesna Rastija
AutorKarolina Vrandečić
AutorJasenka Ćosić
AutorGabriella Kanižai Šarić
AutorIvana Majić
AutorDejan Agić
AutorDomagoj Šubarić
AutorMaja Karnaš
AutorDrago Bešlo
AutorH. Grahmbhatt
AutorM. Komar
Autorova ustanovaSveučilište Josipa Jurja Strossmayera u Osijeku
Fakultet agrobiotehničkih znanosti Osijek
(Zavod za agroekologiju i zaštitu okoliša)
Znanstveno / umjetničko
područje, polje i grana		BIOTEHNIČKE ZNANOSTI
Poljoprivreda (agronomija)
Agrokemija
Sažetak (engleski)
Fluoro-substituted pyrazoles have a wide range of biological activities, such as antibacterial, antiviral, and antifungal activities. The aim of this study was to evaluate the antifungal activities of fluorinated 4,5-dihydro-1H-pyrazole derivatives on four phytopathogenic fungi: Sclerotinia sclerotiorum, Macrophomina phaseolina, Fusarium oxysporum f. sp. lycopersici, and F. culmorum. Moreover, they were tested on two soil beneficial bacteria—Bacillus mycoides and Bradyrhizobium japonicum—as well as two entomopathogenic nematodes (EPNs)—Heterorhabditis bacteriophora and Steinernema feltiae. The molecular docking was performed on the three enzymes responsible for fungal growth, the three plant cell wall-degrading enzymes, and acetylcholinesterase (AChE). The most active compounds against fungi S. sclerotiorum were 2-chlorophenyl derivative (H9) (43.07% of inhibition) and 2,5- dimethoxyphenyl derivative (H7) (42.23% of inhibition), as well as H9 against F. culmorum (46.75% of inhibition). Compounds were shown to be safe for beneficial soil bacteria and nematodes, except for compound H9 on EPN H. bacteriophora (18.75% mortality), which also showed the strongest inhibition against AChE (79.50% of inhibition). The molecular docking study revealed that antifungal activity is possible through the inhibition of proteinase K, and nematicidal activity is possible through the inhibition of AChE. The fluorinated pyrazole aldehydes are promising components of future plant protection products that could be environmentally and toxicologically acceptable.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - domaća recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaInternational Journal o f Molecular Sciences
Brojčani podacivol. 24, br. 11, 9335
p-ISSN1422-0067
DOIhttps://doi.org/10.3390/ijms24119335
URN:NBNurn:nbn:hr:151:314252
Datum objave publikacije2023-05-26
URL dokumentahttps://www.mdpi.com/1422-0067/24/11/9335
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-06-13 14:32:05