prikaz prve stranice dokumenta Effects of Coumarinyl Schiff Bases against Phytopathogenic Fungi, the Soil-Beneficial Bacteria and Entomopathogenic Nematodes: Deeper Insight into the Mechanism of Action
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Effects of Coumarinyl Schiff Bases against Phytopathogenic Fungi, the Soil-Beneficial Bacteria and Entomopathogenic Nematodes: Deeper Insight into the Mechanism of Action
Molecules, 27 (2022), 7; 2196. https://doi.org/10.3390/molecules27072196
Rastija, Vesna; Vrandečić, Karolina; Ćosić, Jasenka; Kanižai Šarić, Gabriella; Majić, Ivana; Agić, Dejan; Šubarić, Domagoj; Karnaš, Maja; Bešlo, Drago; Komar, D.; Molnar, M.

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Rastija, V., Vrandečić, K., Ćosić, J., Kanižai Šarić, G., Majić, I., Agić, D. ... Molnar, M. (2022). Effects of Coumarinyl Schiff Bases against Phytopathogenic Fungi, the Soil-Beneficial Bacteria and Entomopathogenic Nematodes: Deeper Insight into the Mechanism of Action. Molecules, 27. (7). doi: 10.3390/molecules27072196

Rastija, Vesna, et al. "Effects of Coumarinyl Schiff Bases against Phytopathogenic Fungi, the Soil-Beneficial Bacteria and Entomopathogenic Nematodes: Deeper Insight into the Mechanism of Action." Molecules, vol. 27, br. 7, 2022. https://doi.org/10.3390/molecules27072196

Rastija, Vesna, Karolina Vrandečić, Jasenka Ćosić, Gabriella Kanižai Šarić, Ivana Majić, Dejan Agić, Domagoj Šubarić, et al. "Effects of Coumarinyl Schiff Bases against Phytopathogenic Fungi, the Soil-Beneficial Bacteria and Entomopathogenic Nematodes: Deeper Insight into the Mechanism of Action." Molecules 27, br. 7 (2022). https://doi.org/10.3390/molecules27072196

Rastija, V., et al. (2022) 'Effects of Coumarinyl Schiff Bases against Phytopathogenic Fungi, the Soil-Beneficial Bacteria and Entomopathogenic Nematodes: Deeper Insight into the Mechanism of Action', Molecules, 27(7). doi: 10.3390/molecules27072196

Rastija V, Vrandečić K, Ćosić J, Kanižai Šarić G, Majić I, Agić D, i sur.. Effects of Coumarinyl Schiff Bases against Phytopathogenic Fungi, the Soil-Beneficial Bacteria and Entomopathogenic Nematodes: Deeper Insight into the Mechanism of Action. Molecules [Internet]. 28.03.2022. [pristupljeno 26.11.2024.];27(7). doi: 10.3390/molecules27072196

V. Rastija, et al., "Effects of Coumarinyl Schiff Bases against Phytopathogenic Fungi, the Soil-Beneficial Bacteria and Entomopathogenic Nematodes: Deeper Insight into the Mechanism of Action", Molecules, vol. 27, br. 7, Ožujak 2022. [Online]. Dostupno na: https://urn.nsk.hr/urn:nbn:hr:151:413442. [Citirano: 26.11.2024.]

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Naslov (engleski)Effects of Coumarinyl Schiff Bases against Phytopathogenic Fungi, the Soil-Beneficial Bacteria and Entomopathogenic Nematodes: Deeper Insight into the Mechanism of Action
AutorVesna Rastija
AutorKarolina Vrandečić
AutorJasenka Ćosić
AutorGabriella Kanižai Šarić
AutorIvana Majić
AutorDejan Agić
AutorDomagoj Šubarić
AutorMaja Karnaš
AutorDrago Bešlo
AutorD. Komar
AutorM. Molnar
Autorova ustanovaSveučilište Josipa Jurja Strossmayera u Osijeku
Fakultet agrobiotehničkih znanosti Osijek
(Zavod za agroekologiju i zaštitu okoliša)
Znanstveno / umjetničko
područje, polje i grana		BIOTEHNIČKE ZNANOSTI
Poljoprivreda (agronomija)
Agrokemija
Sažetak (engleski)
Coumarin derivatives have been reported as strong antifungal agents against various phytopathogenic fungi. In this study, inhibitory effects of nine coumarinyl Schiff bases were evaluated against the plant pathogenic fungi (Fusarium oxysporum f. sp. lycopersici, Fusarium culmorum, Macrophomina phaseolina and Sclerotinia sclerotiourum). The compounds were demonstrated to be efficient antifungal agents against Macrophomina phaseolina. The results of molecular docking on the six enzymes related to the antifungal activity suggested that the tested compounds act against plant pathogenic fungi, inhibiting plant cell-wall-degrading enzymes such as endoglucanase I and pectinase. Neither compound exhibited inhibitory effects against two beneficial bacteria (Bacillus mycoides and Bradyrhizobium japonicum) and two entomopathogenic nematodes. However, compound 9 was lethal (46.25%) for nematode Heterorhabditis bacteriophora and showed an inhibitory effect against acetylcholinesterase (AChE) (31.45%), confirming the relationship between these two activities. Calculated toxicity and the pesticide-likeness study showed that compound 9 was the least lipophilic compound with the highest aquatic toxicity. A molecular docking study showed that compounds 9 and 8 bind directly to the active site of AChE. Coumarinyl Schiff bases are promising active components of plant protection products, safe for the environment, human health, and nontarget organisms.
Ključne riječi (engleski)
Jezikengleski
Vrsta publikacijeZnanstveni rad - Izvorni znanstveni rad
Status objaveObjavljen
Vrsta recenzijeRecenziran - domaća recenzija
Verzija publikacijeObjavljena verzija rada (izdavačev PDF)
Naslov časopisaMolecules
Brojčani podacivol. 27, br. 7, 2196
p-ISSN1420-3049
DOIhttps://doi.org/10.3390/molecules27072196
URN:NBNurn:nbn:hr:151:413442
Datum objave publikacije2022-03-28
URL dokumentahttps://www.mdpi.com/1420-3049/27/7/2196
Vrsta resursaTekst
Prava pristupaOtvoreni pristup
Uvjeti korištenjaIkona licence Zaštićeno autorskim pravom.
Datum i vrijeme pohrane2024-06-13 15:12:37